Botulinum toxin‐a treatment reduces human mechanical pain sensitivity and mechanotransduction
نویسندگان
چکیده
منابع مشابه
Botulinum toxin‐a treatment reduces human mechanical pain sensitivity and mechanotransduction
The mechanisms underlying the analgesic effects of botulinum toxin serotype A (BoNT-A) are not well understood. We have tested the hypothesis that BoNT-A can block nociceptor transduction. Intradermal administration of BoNT-A to healthy volunteers produced a marked and specific decrease in noxious mechanical pain sensitivity, whereas sensitivity to low-threshold mechanical and thermal stimuli w...
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ژورنال
عنوان ژورنال: Annals of Neurology
سال: 2014
ISSN: 0364-5134,1531-8249
DOI: 10.1002/ana.24122